CHRONIC COMPLICATIONS: DIABETIC FOOT

Authors

  • Juliyeva Yulduz G‘ayrat qizi, Yusupov Dilmurodjon G‘ulomjonovich , Xojibekova Yulduz Zakirovna Andijan Branch of the Republican Specialized Scientific and Practical Medical Center of Endocrinology named after Academician E.Kh. Turakulov

Keywords:

Diabetic foot; Diabetes mellitus; chronic complications; peripheral neuropathy; infection; ulcer; glycemic control; amputation; wound healing; risk factors

Abstract

Diabetic foot is one of the most severe chronic complications of Diabetes mellitus, leading to significant morbidity, reduced quality of life, and increased risk of amputation. This study aimed to evaluate the clinical characteristics, risk factors, and treatment outcomes of patients with diabetic foot complications. A prospective observational study was conducted involving 100 patients with confirmed diabetic foot conditions. Clinical, laboratory, and microbiological assessments were performed, and patients were followed for a period of six months. The results demonstrated that peripheral neuropathy, poor glycemic control, and peripheral arterial disease were the most significant contributing factors to the development and severity of diabetic foot. A high proportion of patients presented with advanced-stage ulcers, indicating delayed diagnosis and treatment. Microbiological analysis revealed a predominance of polymicrobial infections, with Staphylococcus aureus being the most common pathogen. Treatment outcomes showed that early-stage ulcers had significantly better healing rates, while advanced cases were associated with higher rates of surgical intervention and amputation. In conclusion, early diagnosis, strict glycemic control, and a multidisciplinary approach are essential for improving outcomes in patients with diabetic foot. Preventive strategies, including patient education and regular foot care, play a crucial role in reducing the incidence and severity of complications.

Downloads

Download data is not yet available.

References

American Diabetes Association. (2023). Standards of care in diabetes—2023. Diabetes Care, 46(Suppl. 1), S1–S291. https://doi.org/10.2337/dc23-SINT

Armstrong, D. G., Boulton, A. J. M., & Bus, S. A. (2017). Diabetic foot ulcers and their recurrence. The New England Journal of Medicine, 376(24), 2367–2375. https://doi.org/10.1056/NEJMra1615439

Boulton, A. J. M., Vileikyte, L., Ragnarson-Tennvall, G., & Apelqvist, J. (2005). The global burden of diabetic foot disease. The Lancet, 366(9498), 1719–1724. https://doi.org/10.1016/S0140-6736(05)67698-2

International Working Group on the Diabetic Foot (IWGDF). (2019). IWGDF guidelines on the prevention and management of diabetic foot disease. https://iwgdfguidelines.org

Lipsky, B. A., Senneville, É., Abbas, Z. G., et al. (2020). Guidelines on the diagnosis and treatment of foot infection in persons with diabetes. Diabetes/Metabolism Research and Reviews, 36(S1), e3280. https://doi.org/10.1002/dmrr.3280

Prompers, L., Huijberts, M., Apelqvist, J., et al. (2007). High prevalence of ischaemia, infection and serious comorbidity in patients with diabetic foot disease. Diabetologia, 50(1), 18–25. https://doi.org/10.1007/s00125-006-0491-1

Singh, N., Armstrong, D. G., & Lipsky, B. A. (2005). Preventing foot ulcers in patients with diabetes. JAMA, 293(2), 217–228. https://doi.org/10.1001/jama.293.2.217

Downloads

Published

2026-04-29

How to Cite

Juliyeva Yulduz G‘ayrat qizi, Yusupov Dilmurodjon G‘ulomjonovich , Xojibekova Yulduz Zakirovna. (2026). CHRONIC COMPLICATIONS: DIABETIC FOOT. International Multidisciplinary Journal for Research & Development, 13(4), 2447–2453. Retrieved from https://ijmrd.in/index.php/imjrd/article/view/6102