HISTOLOGICAL CHANGES OF EPITHELIAL AND CONNECTIVE TISSUES IN CHRONIC INFLAMMATORY DISEASES AND THEIR CLINICAL SIGNIFICANCE
Abstract
Chronic inflammatory diseases are characterized by persistent tissue damage and repair processes that result in distinct histological alterations of epithelial and connective tissues. These structural changes play a crucial role in disease progression, organ dysfunction, and clinical outcomes. This article aims to analyze the histological features of epithelial and connective tissues in chronic inflammatory conditions and to evaluate their clinical significance. The findings demonstrate that epithelial degeneration, altered regeneration, connective tissue fibrosis, and chronic inflammatory cell infiltration are key morphological hallmarks with important diagnostic and prognostic implications.
Keywords
Histology, chronic inflammation, epithelial tissue, connective tissue, fibrosis, clinical significance
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