NEUROHUMORAL IMBALANCE AND FUNCTIONAL STATUS OF CORONARY GRAFTS IN THE POSTOPERATIVE PERIOD AFTER CORONARY ARTERY BYPASS GRAFTING IN PATIENTS WITH ISCHEMIC HEART DISEASE

Abstract

Background. Ischemic heart disease (IHD) is characterized by high mortality and disability rates among cardiovascular diseases. In cases of multivessel coronary artery disease, coronary artery bypass grafting (CABG) is an effective method of myocardial revascularization. However, persistence or recurrence of clinical symptoms in the postoperative period is not always explained by the anatomical patency of grafts. Recent studies indicate that dysfunction of the sympathoadrenal system (SAS), catecholamine secretion, and their metabolic regulation play an important role in this process.