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Vol. 12 No. 12 (2025)
International Multidisciplinary Journal for Research & Development

Articles

CHANGES IN CEREBROSPINAL FLUID COMPOSITION DURING MENINGITIS AND ITS AGE-RELATED VARIATIONS

Published 2025-12-09

  • Po’latova Sarvinoz Islomjon kizi, Mahmudov Hojimurod Muzaffar ugli

Po’latova Sarvinoz Islomjon kizi, Mahmudov Hojimurod Muzaffar ugli
Student of the Andijan branch of Kokand University

Abstract

Meningitis is an inflammation of the meninges, and cerebrospinal fluid (CSF) analysis is the most reliable criterion for diagnosing and assessing its progression. This article provides a detailed review of changes in CSF composition during bacterial, viral, and fungal meningitis. CSF alterations — including cell count (pleocytosis), protein concentration, glucose level, pressure, and color — vary according to age. In neonates, physiological pleocytosis and elevated protein are observed; in children, glucose decreases rapidly; and in adults, pressure and protein changes are more pronounced. Epidemiological data illustrate the distribution of the disease across different age groups.This article highlights the clinical importance of interpreting CSF findings according to age and serves as a guide for medical students and practicing physicians.,

Keywords

meningitis, cerebrospinal fluid, age-related changes, neonatal meningitis, bacterial meningitis, viral meningitis, fungal meningitis, pleocytosis, decreased glucose, elevated protein, diagnosis.

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