ISOLATION OF GOSSYPOL FROM COTTON PLANT ROOTS AND ITS MODIFICATION

Authors

  • Saidakhmedov Jasurbek Vohidjon ugli Student, Jizzakh Polytechnic Institute
  • Khakberdiyev Shukhrat Makhramovich Associate Professor, Jizzakh Polytechnic Institute

Keywords:

Gossypol, cotton root, extraction, modification, polyphenol, biological activity, supercritical fluid extraction, gossypol derivatives, antimicrobial activity, natural compounds.

Abstract

The isolation and modification of gossypol from the roots of the cotton plant (Gossypium) is of current scientific significance. Gossypol is a natural polyphenolic compound with antiviral, antibacterial, antioxidant, and anticancer properties. This article describes modern extraction methods for obtaining gossypol from cotton roots, including supercritical fluid extraction, ultrasonic-assisted extraction, and microbiological synthesis. During the modification process, methods such as etherification, acylation, halogenation, and the creation of composite materials with polymer matrices are applied to improve the physicochemical properties of gossypol, enhance its biological activity, and reduce its toxicity. The resulting modified gossypol derivatives can find broad applications in pharmaceuticals, cosmetics, agriculture, and industrial sectors.

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References

Биктимиров Л., Зияев Х.Л., Ходжаниязов Б., Зиямов Б., Барам Н.И., Исмаилов А.И. Комплексы производных госсипола с N-поливинилпир-ролидоном // Химия природн. соедин. 1996.-№2.-с.198-201.

Sh. M. Hakberdiev, S. A. Talipov, D. N. Dalimov and B. T. Ibragimov. 2,2-Bis{8-(benzylamino)methylidene]-1,6-dihydroxy-5-isopropyl-3-ethylnaphthalen-7(8H)-one} // Acta Crystallographica Section E69, 2013. о1626-о1627. (№40, Research Gate. IF- 0.34).

K.Ariga, T Kunitake. "Supramolecular Chemistry – Fundamentals and Applications",“Springer” May 2006. .-№4.- Р.69-70.

Руководство по экспериментальному (доклиническому) изучению новых фармакологических веществ, Методы фармакологического доклинического исследования /под ред. Р.У. Хабриева, М., 2005.-с.699-709.

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Published

2025-12-09

How to Cite

Saidakhmedov Jasurbek Vohidjon ugli, & Khakberdiyev Shukhrat Makhramovich. (2025). ISOLATION OF GOSSYPOL FROM COTTON PLANT ROOTS AND ITS MODIFICATION. International Multidisciplinary Journal for Research & Development, 12(12), 259–262. Retrieved from https://ijmrd.in/index.php/imjrd/article/view/4239