IMPACT OF PERSONALIZED COMBINED AEROBIC AND RESISTANCE TRAINING REHABILITATION PROGRAMS ON ADIPOKINE LEVELS (ADIPONECTIN, LEPTIN, RESISTIN) AND INSULIN SENSITIVITY IN PATIENTS WITH METABOLIC SYNDROME
Keywords:
metabolic syndrome, adipokines, adiponectin, leptin, resistin, insulin sensitivity, HOMA-IR, aerobic exercise, resistance training, personalized rehabilitationAbstract
Metabolic syndrome represents a constellation of metabolic abnormalities characterized by insulin resistance, central obesity, dyslipidemia, and hypertension. Adipose tissue-derived adipokines play crucial roles in metabolic regulation, with adiponectin, leptin, and resistin serving as key mediators linking adiposity to systemic metabolic dysfunction.
Downloads
References
Aadahl, M., Kjaer, M., & Jørgensen, T. (2007). Influence of time spent on TV viewing and vigorous intensity physical activity on cardiovascular biomarkers. The Inter99 study. European Journal of Cardiovascular Prevention & Rehabilitation, 14(5), 660-665.
Ahmadizad, S., Haghighi, A. H., & Hamedinia, M. R. (2007). Effects of resistance versus endurance training on serum adiponectin and insulin resistance index. European Journal of Endocrinology, 157(5), 625-631.
Blüher, M., Bullen, J. W., Lee, J. H., Kralisch, S., Fasshauer, M., Klöting, N., ... & Mantzoros, C. S. (2006). Circulating adiponectin and expression of adiponectin receptors in human skeletal muscle: associations with metabolic parameters and insulin resistance. European Journal of Endocrinology, 154(1), 167-173.
Church, T. S., Willis, M. S., Priest, E. L., Lamonte, M. J., Earnest, C. P., Wilkinson, W. J., ... & Barlow, C. E. (2005). Metabolic syndrome and diabetes: prevalence and risk for cardiovascular disease using waist circumference criteria. Nutrition, Metabolism and Cardiovascular Diseases, 15(6), 403-411.
Cordero, A., Masiá, M. D., & Galve, E. (2014). Physical exercise and health. Revista Española de Cardiología, 67(9), 748-753.
Earnest, C. P., Artero, E. G., Sui, X., Lee, D. C., Church, T. S., & Blair, S. N. (2013). Maximal estimated cardiorespiratory fitness, cardiometabolic risk factors, and metabolic syndrome in the aerobics center longitudinal study. Mayo Clinic Proceedings, 88(3), 259-270.
Halverstadt, A., Phares, D. A., Wilund, K. R., Goldberg, A. P., & Hagberg, J. M. (2007). Endurance exercise training raises high-density lipoprotein cholesterol and lowers small low-density lipoprotein and very low-density lipoprotein independent of body fat phenotypes in older men and women. Metabolism, 56(4), 444-450.
Kadoglou, N. P., Iliadis, F., Angelopoulou, N., Perrea, D., Ampatzidis, G., Liapis, C. D., & Alevizos, M. (2007). The anti-inflammatory effects of exercise training in patients with type 2 diabetes mellitus. European Journal of Cardiovascular Prevention & Rehabilitation, 14(6), 837-843.
Kelley, G. A., & Kelley, K. S. (2000). Progressive resistance exercise and resting blood pressure: a meta-analysis of randomized controlled trials. Hypertension, 35(3), 838-843.
Klimcakova, E., Polak, J., Moro, C., Hejnova, J., Majercik, M., Viguerie, N., ... & Langin, D. (2006). Dynamic strength training improves insulin sensitivity without altering plasma levels and gene expression of adipokines in subcutaneous adipose tissue in obese men. The Journal of Clinical Endocrinology & Metabolism, 91(12), 5107-5112.
Kriketos, A. D., Gan, S. K., Poynten, A. M., Furler, S. M., Chisholm, D. J., & Campbell, L. V. (2004). Exercise increases adiponectin levels and insulin sensitivity in humans. Diabetes Care, 27(2), 629-630.
Nassis, G. P., Papantakou, K., Skenderi, K., Triandafillopoulou, M., Kavouras, S. A., Yannakoulia, M., ... & Sidossis, L. S. (2005). Aerobic exercise training improves insulin sensitivity without changes in body weight, body fat, adiponectin, and inflammatory markers in overweight and obese girls. Metabolism, 54(11), 1472-1479.
O'Leary, V. B., Marchetti, C. M., Krishnan, R. K., Stetzer, B. P., Gonzalez, F., & Kirwan, J. P. (2006). Exercise-induced reversal of insulin resistance in obese elderly is associated with reduced visceral fat. Journal of Applied Physiology, 100(5), 1584-1589.
Sillanpää, E., Laaksonen, D. E., Häkkinen, A., Karavirta, L., Jensen, B., Kraemer, W. J., ... & Häkkinen, K. (2009). Body composition, fitness, and metabolic health during strength and endurance training and their combination in middle-aged and older women. European Journal of Applied Physiology, 106(2), 285-296.
Stensvold, D., Tjønna, A. E., Skaug, E. A., Aspenes, S., Stølen, T., Wisløff, U., & Slørdahl, S. A. (2010). Strength training versus aerobic interval training to modify risk factors of metabolic syndrome. Journal of Applied Physiology, 108(4), 804-810.
Tokmakidis, S. P., Zois, C. E., Volaklis, K. A., Kotsa, K., & Touvra, A. M. (2004). The effects of a combined strength and aerobic exercise program on glucose control and insulin action in women with type 2 diabetes. European Journal of Applied Physiology, 92(4-5), 437-442.
Willis, L. H., Slentz, C. A., Bateman, L. A., Shields, A. T., Piner, L. W., Bales, C. W., ... & Kraus, W. E. (2012). Effects of aerobic and/or resistance training on body mass and fat mass in overweight or obese adults. Journal of Applied Physiology, 113(12), 1831-1837.
Yatagai, T., Nagasaka, S., Taniguchi, A., Fukushima, M., Nakamura, T., Kuroe, A., ... & Ishibashi, S. (2003). Hypoadiponectinemia is associated with visceral fat accumulation and insulin resistance in Japanese men with type 2 diabetes mellitus. Metabolism, 52(10), 1274-1278.
Kosimov, I., & Valiyev, R. (2025). BIOIMPEDANCEOMETRY IN ASSESSING THE HEALTH STATUS OF SECONDARY SCHOOL TEACHERS: PERSPECTIVES AND OPPORTUNITIES FOR DISEASE PREVENTION. Journal of Applied Science and Social Science, 1(3), 614-622. https://inlibrary.uz/index.php/jasss/article/view/97244
Butaboev, M. T., Tyan, D. L., Valiyev, R. A., & Pulatov, S. S. (2024). Rehabilitation of patients with digestive diseases. Ethiopian International Journal of Multidisciplinary Research, 11(01), 246-249.
Soliyev, I. M., Kosimov, I. U., & Sodikov, S. A. (2023). NEUROREHABILITATION OF MINOR INJURIES OF THE LUMBOSACRAL SPINE DEPARTMENT IN ATHLETES WITH THE USE OF APPLIED TRAINING SWIMMING FOR STRETCHING. Экономика и социум, (2 (105)), 352-353. https://cyberleninka.ru/article/n/neurorehabilitation-of-minor-injuries-of-the-lumbosacral-spine-department-in-athletes-with-the-use-of-applied-training-swimming-for/viewer
Pulatov, S. S., & Valiev, R. A. (2023). RESPIRATORY PHYSIOTHERAPY INTERVENTIONS IN ACUTE VIRAL RESPIRATORY INFECTIONS: A COMPREHENSIVE THERAPEUTIC EXPLORATION. Экономика и социум, (12 (115)-1), 581-582https://scholar.google.com/scholar?hl=ru&as_sdt=0%2C5&q=RESPIRATORY+PHYSIOTHERAPY+IN
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
