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Vol. 13 No. 01 (2026)
International Multidisciplinary Journal for Research & Development

Articles

BACTERIAL SKIN AND SOFT TISSUE INFECTIONS: ANTIBIOTIC RESISTANCE PATTERNS IN LOCAL CLINICAL PRACTICE

Published 2026-01-05

  • Kamolova Barno Bakhodir kizi

Kamolova Barno Bakhodir kizi
Department of Normal Anatomy, Fergana Medical Institute of Public Health

Abstract

Bacterial skin and soft tissue infections (SSTIs) represent a major cause of outpatient visits and antibiotic prescriptions worldwide. The growing prevalence of antimicrobial resistance has complicated empirical treatment strategies, particularly in regional clinical settings with limited surveillance data. This study aimed to analyze bacterial etiologies and antibiotic resistance patterns among patients presenting with SSTIs in local clinical practice. A retrospective observational study was conducted at the Radeski Skin & Aesthetic Clinic in the Fergana Valley, Uzbekistan. Clinical specimens from patients with purulent and non-purulent SSTIs were cultured, and antimicrobial susceptibility testing was performed using standard laboratory protocols. The most frequently isolated pathogens included Staphylococcus aureus, Streptococcus pyogenes, and Gram-negative organisms such as Escherichia coli and Pseudomonas aeruginosa. High resistance rates were observed for commonly prescribed antibiotics, including penicillins and macrolides, while relatively preserved susceptibility was noted for glycopeptides and select fluoroquinolones.

Keywords

skin infections, antibiotic resistance, bacterial pathogens, antimicrobial susceptibility, local surveillance, clinical dermatology

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