CHEMICAL-TOXICOLOGICAL ANALYSIS OF ALCOHOL POISONING USING A GAS CHROMATOGRAPH (CRYSTALLUX-4000M)

Authors

B.Ibragimov Andijan State Medical Institute

Keywords:

Alcohol poisoning, ethanol, gas chromatography, CrystalLux-4000M, forensic toxicology, blood alcohol concentration.

Abstract

This article presents a modern methodological approach to the chemical-toxicological assessment of alcohol poisoning through the use of gas chromatography, with a focus on the CrystalLux-4000M system. Given the high incidence of acute ethanol intoxication in both forensic and clinical practice, the need for accurate, reproducible, and legally defensible methods for ethanol detection in biological samples is paramount. The article describes in detail the principles of headspace gas chromatography, sample preparation procedures, calibration methods, and forensic interpretation of ethanol concentrations in blood, urine, and vitreous humor. The analytical reliability and sensitivity of the CrystalLux-4000M platform are evaluated in relation to its role in toxicological diagnostics and medicolegal investigations.

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References

Jones, A. W. (2010). Evidence-based survey of the elimination rates of ethanol from blood with applications in forensic casework. Forensic Science International, 200(1-3), 1–20.

Karch, S. B. (2015). Drug Abuse Handbook (3rd ed.). CRC Press.

Oreskovich, M. R., et al. (2021). Interpretation of ethanol levels in postmortem specimens. Journal of Analytical Toxicology, 45(2), 123–130.

Manufacturer’s Manual. CrystalLux-4000M: Chromatographic Solutions for Toxicology. Chromatek, 2020.

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Published

2025-04-24

How to Cite

B.Ibragimov. (2025). CHEMICAL-TOXICOLOGICAL ANALYSIS OF ALCOHOL POISONING USING A GAS CHROMATOGRAPH (CRYSTALLUX-4000M). International Multidisciplinary Journal for Research & Development, 12(04). Retrieved from https://ijmrd.in/index.php/imjrd/article/view/2941